GREEN TEA & DIABETES
inflammation is thought to play an important role in the development of
cardiovascular diseases and many cancers.
Chronic inflammation is also thought to be an important
component of diabetes. Polyphenols
derived from green tea are known
to have significant antioxidant and anti-inflammatory properties, and
research is underway to determine whether or not green tea supplements
favorably impact diseases that are associated, at least in part, with
inflammation. A new
study in the European Journal of Clinical
A total of 60 adult men and women with early diabetes volunteered for this prospective “crossover” study. Half of the volunteers took daily supplements of green tea powder for 2 months, while the other half of the volunteers received no supplements. During the second 2 months of the study, the two groups of study volunteers “crossed over,” and the observation group was then switched to daily green tea supplementation for 2 months, while the group that received green tea supplements during the first half of the study became the observation (or “control”) group. (Crossover studies, such as this one, provide the opportunity for researchers to compare two or more groups’ response to not only initiating therapeutic interventions, but also to assess the effects of stopping such interventions.)
In addition to monitoring blood sugar levels during the course of this clinical research study, the researchers also monitored a marker in the blood, hemoglobin A1C, that reflects the long term adequacy of diabetes control. This study also assessed the volunteers for potential changes in weight, body fat levels, blood pressure, fasting blood glucose levels, cholesterol levels (including HDL and LDL), and C-reactive protein levels (a blood marker of inflammation).
Although none of the other parameters changed significantly in the volunteers who were assigned to take green tea supplements, a significant decrease in hemoglobin A1C levels was observed in response to daily green tea supplementation.
Although this brief study cannot tell us what the long term health impact of green tea is on patients with early diabetes, it is nonetheless intriguing that daily green tea supplementation, when taken for only two months, was able to reduce hemoglobin A1C levels. The next logical step would be a prospective, randomized, double-blinded clinical study with a longer duration of follow-up.
BREASTFEEDING & ADULT CHOLESTEROL LEVELS
Many claims have been made regarding the putative lifelong benefits of breastfeeding. Now, a new review study in the American Journal of Clinical Nutrition assesses the cumulative clinical data regarding the long term effects of breastfeeding on adult cholesterol levels. In this paper, data from 17 previously published research studies, encompassing a total of 17,498 patients, was reviewed and analyzed. Altogether, 12,890 study volunteers reported being breastfed as babies, while 4,608 were primarily fed with baby formula during infancy. All of these adult volunteers had blood cholesterol levels measured as part of these 17 clinical studies. When analyzing differences in blood cholesterol levels among the 17 previously published clinical studies, the authors of this new review study adjusted their analysis to correct for differences in age, socioeconomic status, body weight and smoking status among the study volunteers.
On average, blood cholesterol levels were significantly lower among the volunteers who reported being breastfed as infants, when compared to the volunteers who were formula-fed. Among the 7 previous studies that analyzed adult cholesterol levels in volunteers who reported being either exclusively breastfed or exclusively formula-fed, the difference in blood cholesterol levels between breastfed volunteers and formula-fed volunteers was even greater and more consistent, favoring lower cholesterol levels in adults who were breastfed as babies.
OIL & SENILE
OIL & SENILE
degeneration (SND) is the second most common cause of blindness in the
A new study, published in the American Journal of Clinical Nutrition, assessed the impact of eating oily fish on the incidence of SMD. In this study, volunteers 65 years of age and older underwent extensive dietary surveys to identify the frequency of oily fish consumption. These volunteers also underwent eye examinations to assess for signs of SMD.
Among the 2,275 volunteers, 105 were diagnosed with early or late SMD. Based upon dietary survey results, the authors of this study determined that eating oil-rich fish at least once per week appeared to be associated with a 50% reduction in the risk of developing SMD. Among those patients reporting the highest levels of oily fish intake, the risk of SMD was reduced by about 70%.
Dr. Wascher is an oncologic surgeon, professor of surgery, a widely published author, and the Director of the Division of Surgical Oncology at Newark Beth Israel Medical Center
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Copyright 2008. Robert A. Wascher, MD, FACS. All rights reserved.
Dr. Wascher's Archives:
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4-6-2008: Human Papilloma Virus (HPV), Pap Smear Results & Cervical Cancer; Human Papilloma Virus (HPV) Infection & Oral Cancer; Hormone Replacement Therapy (HRT) & the Risk of Gastroesophageal Reflux Disorder (GERD)
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